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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCRIB All Species: 7.58
Human Site: S1225 Identified Species: 20.83
UniProt: Q14160 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14160 NP_056171.2 1630 174885 S1225 R N S L E S I S S I D R E L S
Chimpanzee Pan troglodytes XP_520005 1359 146423 G999 T G A A G R D G R L R V G L R
Rhesus Macaque Macaca mulatta XP_001109225 524 59241 T164 E L R E N L L T Y L P D S L T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q80U72 1612 174041 S1211 R N S L E S I S S I D R E L S
Rat Rattus norvegicus P70587 1495 167465 M1130 S L A S S T E M A M F R R V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q4H4B6 1724 189501 K1273 G P L K L D Y K T L A A L P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRY7 1851 200421 L1470 A S E T G S E L S Q S Q S V S
Honey Bee Apis mellifera XP_397110 1709 188206 T1263 K G N P L D H T D E G V F I S
Nematode Worm Caenorhab. elegans O61967 699 77331 V339 G N C K S L T V L S L R Q N I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58 22.6 N.A. N.A. 86.3 23.9 N.A. N.A. N.A. N.A. 60.6 N.A. 33.4 35.3 20.3 N.A.
Protein Similarity: 100 63.5 27.9 N.A. N.A. 89.7 39.2 N.A. N.A. N.A. N.A. 72.7 N.A. 48.7 51.9 30.8 N.A.
P-Site Identity: 100 6.6 6.6 N.A. N.A. 100 13.3 N.A. N.A. N.A. N.A. 0 N.A. 20 6.6 13.3 N.A.
P-Site Similarity: 100 20 33.3 N.A. N.A. 100 46.6 N.A. N.A. N.A. N.A. 20 N.A. 40 33.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 23 12 0 0 0 0 12 0 12 12 0 0 0 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 23 12 0 12 0 23 12 0 0 0 % D
% Glu: 12 0 12 12 23 0 23 0 0 12 0 0 23 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 0 12 0 0 % F
% Gly: 23 23 0 0 23 0 0 12 0 0 12 0 12 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 23 0 0 23 0 0 0 12 12 % I
% Lys: 12 0 0 23 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 23 12 23 23 23 12 12 12 34 12 0 12 45 0 % L
% Met: 0 0 0 0 0 0 0 12 0 12 0 0 0 0 0 % M
% Asn: 0 34 12 0 12 0 0 0 0 0 0 0 0 12 0 % N
% Pro: 0 12 0 12 0 0 0 0 0 0 12 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 12 12 0 0 % Q
% Arg: 23 0 12 0 0 12 0 0 12 0 12 45 12 0 12 % R
% Ser: 12 12 23 12 23 34 0 23 34 12 12 0 23 0 56 % S
% Thr: 12 0 0 12 0 12 12 23 12 0 0 0 0 0 23 % T
% Val: 0 0 0 0 0 0 0 12 0 0 0 23 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _